Sarafloxacin hydrochloride_91296-87-6_DataSheet_MedChemExpress

Product Name:

Sarafloxacin hydrochloride CAS No.:

91296-87-6Cat.No.:HY-B0343A Product Data Sheet

Cat. No.:

HY B0343A MWt:

421.83Formula:

C20H18ClF2N3O3Purity :>98%

DMSO 1mg/mL;Water <1mg/mL Solubility:Mechanisms:

Biological Activity:

S f

Pathways:Anti-infection; Target:Antibacterial DMSO 1 mg/mL; Water <1 mg/mL

Sarafloxacin hydrochloride is a quinolone antibiotic drug.

Target: Antibacterial sarafloxacin hydrochloride is a fluoroquinolone antibiotic registered for use against poultry diseases.Sarafloxacin treatment demonstrated mineralization to 14CO2 amounting to 0.58%, 0.49%, and 0.57% in loam, silt loam, and sandy loam soils, respectively, at the termination of the test [1]. The inhibitory level of sarafloxacin for the tested bacteria was strain dependent. It appeared that in broth culture Escherichia coli isolates were sensitive to sarafloxacin concentrations 5‐fold lower than the concentrations present in the simulated gut model, suggesting that sarafloxacin may be partially unavailable due to absorption to organic matter in the model [2]Administering Sarafloxacin References:

[1]. Marengo, J.R., et al., Aerobic biodegradation of (14C)‐sarafloxacin hydrochloride in soil.

Environmental Toxicology and Chemistry, 1997. 16(3): p. 462-471.[2]. McConville, M.L., et al., Effects of sarafloxacin hydrochloride on human enteric bacteria under unavailable due to absorption to organic matter in the model [2]. Administering Sarafloxacin

hydrochloride in the feed for 5 d at a dose of 10 or 12.5 mg/kg of fish proved efficacious in treating cha...

simulated human gut conditions. Vet Q, 1995. 17(1): p. 1-5.

[3]. Johnson, M.R., K.L. Smith, and C.R. Boyle, Field efficacy trials of the antibacterial sarafloxacin-hydrochloride (A-56620) for treatment of Edwardsiella ictaluri infections in channel catfish. Journal of

aquatic animal health, 1992. 4(4): p. 244-251.Caution: Not fully tested. For research purposes only

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